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目的为了探讨男性不育症患者的发病机理。方法通过检测20例对照组(生育组)与140例观察组(不育组)精浆中的果糖、锌、酸性磷酸酶、中性α-葡糖苷酶、弹性硬蛋白酶、LDH-X、顶体酶,综合分析两组精浆中的化学成分变化。结果不育症组精浆中的果糖、锌、中性α-葡糖苷酶、顶体酶每次射精含量都显著低于生育组(P<0.01);酸性磷酸酶、LDH-X每次射精含量稍低于生育组,但无统计学意义(P>0.01);而不育组弹性硬蛋白酶浓度明显高于生育组(P<0.01)。结论精浆中的果糖、锌、酸性磷酸酶、中性α-葡糖苷酶、弹性硬蛋白酶、LDH-X、顶体酶浓度可以用来综合评估男性患者的生育能力。
Objective To explore the pathogenesis of male infertility. Methods The serum levels of fructose, zinc, acid phosphatase, neutral α-glucosidase, elastase, LDH-X in the seminal plasma of 20 cases of control group (fertility group) and 140 cases of observation group Body enzymes, a comprehensive analysis of changes in the two groups of seminal plasma chemical composition. Results The contents of fructose, zinc, neutral α-glucosidase and acrosin per seminal ejaculation in infertile group were significantly lower than those in reproductive group (P <0.01). Acid phosphatase, LDH-X, Content was slightly lower than the fertility group, but not statistically significant (P> 0.01), while the concentration of elastase in infertile group was significantly higher than that of the reproductive group (P <0.01). Conclusion The concentrations of fructose, zinc, acid phosphatase, neutral α-glucosidase, elastase, LDH-X and acrosin in seminal plasma can be used to evaluate the fertility of male patients.