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本文用磷酸组织胺球蛋白治疗31例美尼尔氏病与12例非美尼尔氏病的对照病例。治疗结果说明,磷酸组织胺球蛋白对美尼尔氏病疗效显著,不仅可以控制美尼尔氏病发作时的眩晕、耳鸣、耳闭等症状,而且明显减少急性发作次数,延长发作间歇期。虽然停药数月后仍有复发倾向,但发作时眩晕程度明显减轻。从其显著疗效考虑,作者等认为美尼尔氏病的病因与变态反应有关。并且推测其对美尼尔氏病的疗效机制,可能与解除对透明质酸酶的抑制作用有关。
In this paper, histamine amidoglobin treatment of 31 cases of Meniere’s disease and 12 cases of non-Meniere’s control cases. Treatment results show that histamine phosphoinositide on the significant effect of Meniere’s disease, not only can control the onset of Meniere’s dizziness, tinnitus, ear and other symptoms, but also significantly reduce the number of acute attacks, prolonged intermission period. Although withdrawal tended to relapse after several months, the degree of vertigo was significantly reduced during the episode. Considering its significant curative effect, the authors believe that the etiology of Meniere’s disease is related to the allergic reaction. And speculated that its mechanism of action on Meniere’s disease, may be related to the lifting of hyaluronidase inhibition.