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本文测定了中国非胰岛素依赖型糖尿病病人(NIDDM;男13名,女10名)和非糖尿病对照组(男8名,女10名)血浆和极低密度脂蛋白(VLDL)中Apo CⅠ、CⅡ和CⅢ水平。男性病人组ApoCⅠ水平、Apo CⅠ/TG(TG指甘油三酯)、ApoCⅡ/TG和Apo CⅠ/CⅢ比值均显著低于男性对照组,而女性病人组Apo CⅡ水平显著高于女性对照组;男性病人组空腹血糖与女性病人组者相似。因此,男性病人较高的VLDL水平可能与血浆和VLDL中Apo CⅠ、CⅡ和CⅢ的不正常组成有关,而与高血糖本身无关。
In this study, we measured the levels of Apo CⅠ, CⅡ (CⅡ) in plasma and very low density lipoprotein (VLDL) in non-insulin dependent diabetes mellitus patients (NIDDM, 13 males and 10 females) and non-diabetic controls (8 males and 10 females) And CⅢ level. The ApoCⅠ level, Apo CⅠ / TG (TG triglyceride), ApoCⅡ / TG and Apo CⅠ / CⅢ ratio in male patients were significantly lower than those in male controls, while those in female patients were significantly higher than those in female controls The fasting blood glucose in the patient group was similar to that in the female patient group. Therefore, the higher VLDL levels in male patients may be related to the abnormal components of Apo CⅠ, CⅡ and CⅢ in plasma and VLDL, but not hyperglycemia itself.