伴未成熟性白质损害的早产患者视野缺损的多病例研究

• 作 者: Jacobson L. Flodmark O. Martin L. 杨秀梅
• 机 构: Department of Clinical Neuroscience Ophthalmology and Vision Karolinska Institute,St.Erik's Eye Hosp
• 出 处: 世界核心医学期刊文摘.眼科学分册
• 发表日期: 2006年09期
• 关键词: 视野缺损 成熟性 病例研究 视野检查 视功能 眼底照相 早产史 认知功能

Purpose:White matter damage of immaturity may affect visual,motor and cognitive functions.This multiple-case study presents standardized perimetry results in six teenagers and young adults born prematurely with visual dysfunction due to white matter damage of immaturity of pre-or perinatal origin.Methods:Six subjects,aged 13-25 years,born at a gestational age of 28-34 weeks,with white matter damage of immaturity documented by MRI,and optic disc appearances documented by fundus photography,were examined with manual and computerized quantitative perimetry.Results:All subjects had subnormal visual field(VF)function,although the depth and extension of the VF defects differed between subjects.The inferior VF function was more deviant than the superior in all cases.The concordance between the VF defects detected with the different techniques was good,although the static computerized techniques revealed slightly more abnormality.Conclusion:White matter damage of immaturity may affect the VF.The lower VF is often more affected than the upper.The abnormalities can be demonstrated by both manual and computerized perimetry.

Purpose: White matter damage of immaturity may affect visual, motor and cognitive functions. These multiple-case study presents standardized standardized perimetry results in six teenagers and young adults born prematurely with visual dysfunction due to white matter damage of immaturity of pre-or perinatal origin. Methods: Six subjects, aged 13-25 years, born at a gestational age of 28-34 weeks, with white matter damage of immaturity documented by MRI, and optic disc appearances documented by fundus photography, were examined with manual and computerized quantitative perimetry. Results: All subjects had subnormal visual field (VF) function, although the depth and extension of the VF defects differed between subjects. The inferior VF function was more deviant than the superior in all cases. Concordance between the VF defects detected with the different techniques was good, although the static computerized techniques revealed slightly more abnormality. Conlusion: White matter damage of immaturity may affect the VF.T he lower VF is often more affected than the upper.The abnormalities can be demonstrated by both manual and computerized perimetry.