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每年有数以百万计的抗心律失常药物处方用于治疗室性心律失常。其中大部分是治疗无症状性复杂室性心律失常和器质性心脏病,即所谓“潜在恶性”或“潜在致命性”心律失常。但治疗这类心律失常对患者的效益尚未证实。为此,作者研究了八种抗心律失常药物疗效与左室功能的关系。方法室性心律失常患者246例,男158,女88例,平均年龄58±11岁,其中器质性心脏病192例,无明确器质性心脏病54例。190例为非持续性室性心动过速(VT),17例有持续性 VT 史。其余53例为有症状
Every year millions of antiarrhythmic prescriptions are used to treat ventricular arrhythmias. Most of these are the treatment of asymptomatic complex ventricular arrhythmias and structural heart disease, the so-called “potentially malignant” or “potentially fatal” arrhythmias. However, the treatment of such arrhythmias in patients with the effectiveness has not been confirmed. To this end, the authors studied the efficacy of eight anti-arrhythmic drugs in relation to left ventricular function. Methods 246 cases of ventricular arrhythmia, 158 males and 158 females, mean age 58 ± 11 years, of which 192 cases of organic heart disease, 54 cases without definite organic heart disease. 190 cases of non-sustained ventricular tachycardia (VT), 17 cases of persistent VT history. The remaining 53 cases were symptomatic