论文部分内容阅读
即使广泛地进行卡介苗(BCG)预防接种,结核病在发展中国家的发病率仍较高(4‰),我国1979年全国抽样调查的结果表明,患病率为7.17‰。在寻求新的预防方法方面,国外进行了大量研究工作,经多年的实践证明,异烟肼预防治疗,在结核病好发人群,特别是儿童或青少年中对降低发病率可以起到显著的作用。此种方法在国内也用于临床,并收到良好效果。为了在基层推广这一预防方法,本文拟以药物预防结核病的效果、服药对象、给药方法及不良反应等几个问题概述如下。
Even though BCG vaccination is widespread, the incidence of tuberculosis in developing countries is still high (4 ‰). The result of a national sample survey in 1979 in China showed that the prevalence was 7.17 ‰. In the search for new prevention methods, a great deal of research work abroad has been carried out. After many years of practice, it has been proved that isoniazid prophylaxis can play a significant role in reducing morbidity in people with TB, especially children or adolescents. This method is also used clinically in the country, and received good results. In order to promote this prevention method at the grassroots level, this article intends to summarize the following issues with regard to the drug effect of preventing tuberculosis, the object of administration, the method of administration and adverse reactions.