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目的:分析对维持性血液透析肾性贫血患者使用蔗糖铁联合左卡尼汀辅助促红细胞生成素的效果。方法:收集2013年3月至2016年7月高要区人民医院收治的维持性血液透析肾性贫血患者共86例,根据随机化分组原则分为对照组和观察组各43例,对照组的治疗药物为蔗糖铁联合促红细胞生成素,观察组则联合使用左卡尼汀,将两组患者的疗效、促红细胞生成素使用情况、不良反应发生率进行观察和对比。结果:观察组治疗后的总有效率优于对照组;就促红细胞生成素使用情况而言,观察组的用量显著低于对照组;而在不良反应发生率方面,观察组显著低于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:在维持性血液透析肾性贫血患者的治疗过程中,蔗糖铁联合左卡尼汀辅助促红细胞生成素能够使患者获得更佳疗效,并降低促红细胞生成素的用量,减少药物的不良反应。
OBJECTIVE: To analyze the effect of erythropoietin supplementation with sucrose and iron combined with levocarnitine on maintenance hemodialysis patients with renal anemia. Methods: A total of 86 patients with maintenance hemodialysis and renal anemia who were treated in Gaoyao District People’s Hospital from March 2013 to July 2016 were collected. According to the principle of randomization, the patients were divided into control group and observation group, 43 cases in each group. The treatment drug was sucrose iron combined with erythropoietin, the observation group was combined with levocarnitine, the efficacy of the two groups of patients, the use of erythropoietin, the incidence of adverse reactions were observed and compared. Results: The total effective rate of the observation group was better than that of the control group. For the use of erythropoietin, the dosage of the observation group was significantly lower than that of the control group. In the incidence of adverse reactions, the observation group was significantly lower than the control group , The difference between groups was statistically significant (P <0.05). CONCLUSIONS: In the course of treatment of maintenance hemodialysis patients with renal anemia, sucrose iron combined with levocarnitine-assisted erythropoietin can achieve better efficacy and reduce the dosage of erythropoietin in patients with adverse drug reactions .