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目的:分析我院药品不良反应(ADR)的发生情况,确保患者用药安全。方法:对我院2009～2011年收集到的200例ADR报告进行统计、分析。结果:200例ADR中,60岁以上患者发生率最高,占28.50%。由抗菌药物引发ADR的比例最高,占31.50%。注射给药途径是引发药品不良反应的主要途径,占90.00%。ADR的临床表现以皮疹、瘙痒等皮肤及附件损害为主,其次为全身症状及消化系统损害。结论不良反应的发生和很多因素有关,应重视医院ADR的报告及监测工作,提高合理用药水平,避免或减少药品不良反应。
Objective: To analyze the incidence of adverse drug reaction (ADR) in our hospital to ensure the safety of patients. Methods: The data of 200 cases of ADR collected in our hospital from 2009 to 2011 were analyzed. Results: Among the 200 cases of ADR, the incidence was highest in patients over 60 years old, accounting for 28.50%. The highest proportion of ADRs was caused by antibiotics, accounting for 31.50%. Injection route of administration is the main route leading to adverse drug reactions, accounting for 90.00%. The clinical manifestations of ADR to skin rash, itching and other accessories and the main damage, followed by systemic symptoms and digestive system damage. Conclusions The occurrence of adverse reactions is related to many factors. It is necessary to pay attention to the report and monitoring of ADR in hospitals, improve the rational use of drugs, and avoid or reduce adverse drug reactions.