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目的探讨美托洛尔联合米力农治疗顽固性心绞痛的临床疗效方法用美托洛尔联合米力农治疗58例顽固心绞痛患者,使患者心率维持于40～50次/min或卧位时收缩压90mmHg左右,观察治疗前后心绞痛发作频率、程度,治疗前、后行24h动态心电图(DCG)检查,计算24h心肌缺血发作的次数和总时间。结果治疗后,患者平均心率、缺血次数、24h缺血总时间、12导联ST段压低总和较治疗前均明显降低。结论美托洛尔联合米力农治疗顽固性心绞痛,临床安全有效。
Objective To investigate the clinical efficacy of metoprolol in combination with milrinone in the treatment of refractory angina pectoris. Methods Metoprolol combined with milrinone was used to treat 58 patients with stubborn angina pectoris. The heart rate was maintained at 40-50 beats / min or in the supine position Pressure 90mmHg or so, observe the frequency of angina pectoris before and after treatment, before and 24 hours after treatment dynamic electrocardiogram (DCG) check, 24h calculated myocardial ischemic attack frequency and total time. Results After treatment, the mean heart rate, the number of ischemia, the total time of 24h ischemia, and the decrease of ST-segment depression in 12-lead group were significantly lower than those before treatment. Conclusion Metoprolol combined with milrinone in the treatment of refractory angina pectoris is clinically safe and effective.