【摘 要】
：
一种鲭鱼的匀浆在pH 3、25℃时与亚硝酸钠温育3小时,其乙醚提取物对沙门氏菌TA1535具有致突变活性。10μl的提取液在不加S-9混合液时产生125个回变菌落。用此种含有突变物质
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一种鲭鱼的匀浆在pH 3、25℃时与亚硝酸钠温育3小时,其乙醚提取物对沙门氏菌TA1535具有致突变活性。10μl的提取液在不加S-9混合液时产生125个回变菌落。用此种含有突变物质的提取液对Wistar大鼠每周灌胃三次,持续6个月,前2个月每次灌胃量0.5 ml,后4个月每次1.0 ml。在饲养12～18个月后,
A homogenate of mackerel was incubated with sodium nitrite for 3 hours at pH 3,25 ° C and its ether extract had mutagenic activity against Salmonella TA1535. Ten μl of the extract produced 125 replicate colonies without S-9 cocktail. Wistar rats were intragastrically administered three times a week for 6 months with this extract containing the mutagenized substance. The first 2 months were 0.5 ml for each administration and 1.0 ml for 4 months. After feeding for 12 to 18 months,
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