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在妊娠期,由于激素平衡的改变引起糖原在阴道细胞内的堆积,故阴道念珠菌病特别常见,妊娠的最后几周尤多。而且新生儿也可因通过感染的产道时受污染而发生皮肤念珠菌病和鹅口疮,早产或虚弱的新生儿甚至可引起全身性霉菌感染。咪唑(Imidazole)衍生物是十分强有力的抗霉菌药,常用于妊娠期,最近已有一些用益康唑阴道栓治疗妊娠期阴道念珠菌病获得良效的报道。本文报告了对117例妊娠期阴道念珠菌病妇女用益康唑阴道栓治疗的结果。病人中有近50％是妊娠的最后一个月,她们均接受一个疗程——用益康唑阴道栓(每一栓剂含益康唑150mg)塞入阴道,每晚一次,连续用3天,疗程结束后一周及分娩时再重复临床
During pregnancy, vaginal candidiasis is particularly common due to the accumulation of glycogen in the vaginal cells due to changes in hormone balance, particularly in the last weeks of pregnancy. Neonates can also develop cutaneous candidiasis and thrush due to contamination while passing through the infected birth canal. Premature or weak neonates can even cause systemic fungal infections. Imidazole derivatives are very potent antimycotic drugs commonly used in pregnancy. Recently, some reports on the efficacy of vaginal suppository with econazole in the treatment of vaginal candidiasis in pregnancy have been reported. This article reports the results of 117 women with gestational vaginal candidiasis treated with econazole vaginal suppository. Nearly 50% of patients are in the last month of pregnancy, and they both receive a course of treatment - with econazole vaginal suppository (each suppository containing econazole 150mg) into the vagina, nightly, for 3 consecutive days, the end of treatment After a week and childbirth and then repeat the clinical