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目的通过对原发性肝癌(PHC)两种介入治疗方法的疗效比较,评估其应用价值。材料和方法从1985年4月~1997年12月,我院用肝动脉化疗、栓塞术治疗172例中、晚期肝癌,根据不同的治疗方法,分为两组。A 组:107例,为动脉内抗癌药灌注(TAI);B 组:65例,为碘化油与抗癌药再加明胶海棉动脉栓塞(TAE)。对两组的肿瘤直径缩小率、甲胎蛋白下降情况及生存期进行观察对比。结果 TAE 组肿瘤直径缩小率、甲胎蛋白下降情况及生存期明显优于 TAI 组(P<0.01)。结论根据患者的具体情况,恰当选择和施行 TAE、TM,有助于提高中、晚期肝癌患者的生存期和生存质量。
Objective To evaluate the application value of two interventional treatment methods for primary liver cancer (PHC). Materials and Methods From April 1985 to December 1997, our hospital used hepatic arterial chemotherapy and embolization to treat 172 cases of advanced and advanced liver cancer. According to different treatment methods, the two groups were divided into two groups. Group A: 107 cases were intraarterial anti-cancer drug infusion (TAI); Group B: 65 cases, iodized oil and anticancer drugs plus gelatin sponge arterial embolization (TAE). The comparison of tumor diameter reduction rate, alpha-fetoprotein decrease, and survival period was observed in both groups. Results The tumor diameter reduction, alpha fetoprotein decrease, and survival time were significantly better in the TAE group than in the TAI group (P<0.01). Conclusions According to the specific conditions of patients, proper selection and implementation of TAE and TM can help improve the survival and quality of life of patients with hepatocellular carcinoma.