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目的 探讨超声引导下多电极射频疗法对原发性肝癌的治疗效果。方法 在超声引导下 ,对 5 4例原发性肝癌患者行多电极射频治疗 ,观察治疗前后肿瘤声像图表现、大小、血流频谱、AFP水平及生存率变化。结果 多电极射频治疗后 ,肿瘤区由术前等或低或略高回声转变成强弱不等点状回声 ,术后 1～ 2周 46例病灶内动静脉血流频谱几乎消失。术后 2～ 6周 3 8例AFP阳性患者转阴 3 1例 ,下降 4例 ,有效率 92 .1%。术后 3个月复查超声或CT显示 47例 ( 87.0 % )患者肿瘤体积缩小 2 5 %以上。所有患者均得到随访 ,5 2例患者存活超过 3个月 ,最长已达 7个月。结论 多电极射频疗法是治疗原发性肝癌新的有效方法。
Objective To investigate the therapeutic effect of ultrasound-guided multi-electrode radiofrequency therapy on primary liver cancer. Methods Fifty-four patients with primary hepatocellular carcinoma underwent multi-electrode radiofrequency ablation guided by ultrasound. The appearance, size, blood flow spectrum, AFP level and survival rate before and after treatment were observed. Results After multi-electrode radiofrequency ablation, the tumor area changed from low or slightly high echogenicity to point-like echogenicity before and after operation. The spectrum of arteriovenous blood flow disappeared in 46 lesions 1-2 weeks after operation. Three to eight weeks after operation, 38 cases of AFP positive patients were negative in 3 cases, 4 cases decreased, with an effective rate of 92.1%. Three months after the operation, ultrasound or CT showed that the tumor volume of 47 patients (87.0%) was reduced by 25% or more. All patients were followed up, 52 patients survived more than 3 months, up to a maximum of 7 months. Conclusion Multi-electrode radiofrequency therapy is a new and effective method for the treatment of primary liver cancer.