卵巢恶性混合性生殖细胞瘤(无性细胞瘤合并内胚窦瘤)一例报告

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患者女性,26岁,未婚。右下腹痛26小时伴压痛、反跳痛,拟诊急性兰尾炎入院。术中见右侧附件肿块扭转破裂,作肿块单纯切除术。确诊后转上海某医院妇产科再次行盆腔根除术。经随访患者于术后七个月死于全身转移。病理肉眼观察卵巢肿块7×6×4 cm大小,切面出血,坏死、部分囊性变,质脆。另有一小结节3×2×2 cm大小,切面淡黄色,海绵状。镜下:(1)无性细胞瘤瘤细胞圆而大,大小一致,胞浆透明或颗粒状呈嗜碱性,胞核圆形,染色质不规则凝集,核仁明显。瘤细胞排列 Patient female, 26 years old, unmarried. Right lower abdominal pain 26 hours with tenderness, rebound tenderness, diagnosis of acute mansony admitted. Surgery, see the right side of the annex to reverse the rupture of the tumor mass for simple excision. After the diagnosis transferred to a hospital in Shanghai obstetrics and gynecology again pelvic eradication. Follow-up patients died of systemic metastases seven months after surgery. Pathological gross observation of ovarian tumor size 7 × 6 × 4 cm, section bleeding, necrosis, some cystic changes, crisp. Another small nodules 3 × 2 × 2 cm size, section pale yellow, sponge-like. Microscopically, (1) melanoma cells were round and large, consistent in size, cytoplasm transparent or granular basophilic, round nucleus, irregular chromatin condensation, obvious nucleoli. Tumor cells arranged
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