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The magnetic nanoparticles supported silica sulfuric acid was used as an efficient catalyst for the synthesis of pyrimido[4,5-b]quinoIines and indeno fused pyrido(2,3-d]pyrimidines in water.The desired products were obtained in excellent yields.Fe_3O_4@SiO_2-SO_3H was readily recovered using an external magnet and could be reused several times without significant loss of reactivity.
The magnetic nanoparticles supported silica sulfuric acid was used as an efficient catalyst for the synthesis of pyrimido [4,5-b] quinoIines and indeno fused pyrido (2,3-d] pyrimidines in water. The desired products were obtained in excellent yields. Fe_3O_4 @ SiO_2-SO_3H was suddenly recovered using an external magnet and could be reused several times without significant loss of reactivity.