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目的:对宁河县适龄儿童含麻疹成分疫苗免疫后抗体阳性率进行监测分析,为今后的免疫服务和制定相关政策提供科学依据。方法:随机选取部分城镇地区和农村地区接种过含麻疹成分疫苗的适龄儿童,对其家长进行告知,采集儿童指尖血,ELISA法检测麻疹抗体IgG。结果:共检测1 081例适龄儿童的麻疹抗体IgG,1 070例阳性,阳性率98.98%。男性596例,589例阳性,阳性率98.82%;女性485例,481例阳性,阳性率99.18%。9月龄~组阳性率为98.65%,24月龄~组为99.22%。接种1、2、3剂次的阳性率分别为98.22%、99.03%和99.70%。城镇地区阳性率98.36%,农村地区为99.30%。结论:宁河县适龄儿童含麻疹成分疫苗免疫后抗体阳性率高,不同性别、不同年龄组、不同接种剂次、不同地区的阳性率差异无统计学意义;个别儿童接种疫苗后未能产生抗体,存在免疫失败现象。
OBJECTIVE: To monitor and analyze the antibody positive rate of measles vaccine in children of school age in Ninghe County, and provide scientific basis for future immunization service and formulation of relevant policies. Methods: Selected children from urban areas and rural areas who were vaccinated with measles-containing vaccine were randomly selected to inform their parents about the finger-tip blood of children and IgG was detected by ELISA. Results: A total of 1 081 measles antibody were detected in children of school age, 1 070 cases were positive, the positive rate was 98.98%. 596 males, 589 cases were positive, the positive rate was 98.82%; 485 cases of women, 481 cases were positive, the positive rate was 99.18%. The positive rate of 9-month-old group was 98.65% and that of 24-month-old group was 99.22%. The positive rates of inoculation for 1, 2 and 3 doses were 98.22%, 99.03% and 99.70% respectively. The positive rate was 98.36% in urban areas and 99.30% in rural areas. Conclusion: The positive rate of measles vaccine immunization of children of school-age children in Ninghe county is high, and there is no significant difference in the positive rates of different sexes, different age groups, different inoculation times and different regions. The individual vaccines failed to produce antibodies , There is immune failure phenomenon.