Role of gamma-delta T cells in liver inflammation and fibrosis

• 作 者: Linda Hammerich Frank Tacke
• 机 构: DepartmentofMedicineⅢ
• 出 处: 世界胃肠病理生理学杂志：英文版（电子版）
• 发表日期: 2014年2期
• 关键词: LIVER FIBROSIS LIVER CIRRHOSIS INTERLEUKIN-17 Gamma/delta T cells CYTOKINES Live
• 基金项目: Supported by The German Research Foundation,No.DFG Ta434/2-1 and SFB/TRR57,the Interdisciplinary Center for Clinical Research(IZKF) Aachen

Conventional adaptive T cell responses contribute to liver inflammation and fibrogenesis,especially in chronic viral infections and autoimmune hepatitis.However,the role of unconventional gamma-delta(γδ)T cells in liver diseases is less clear.In the past