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1982年3月7日～12日在美国加利福尼亚州举行了一次关于干扰素的化学和生物学的国际论文报告会,报道了以下内容:干扰素(IFN_s)的结构功能及其基因,研究IFN作用的动物及体外模型,人类疾病中的IFN_s,重组的和天然的IFN_s,以及天然IFN_s的临床试验。 Weissman报告,人的IFN-α有14种不同的基因,已知其中3种假基因(Pseudogenes)的结构,另外4种杂交基因的结构还不清楚。现在已建立了小鼠LFN-α的克隆。他认为,尽管在四十亿年前IFN-α和IFN-β就已分化了,但人和小鼠IFN-α的分化则是七亿年前的事。Goeddel已建立了4株小牛IFN-α的基因克隆和大肠肝菌(EC)及猴细胞的IFN-γ克隆。此基因位于人的第12条染
An international paper on chemistry and biology of interferon was held in California, USA from March 7 to March 12, 1982. It reported the following: the structural function of interferon (IFN) and its genes, the effects of IFN Animal and in vitro models, IFN-s in human disease, recombinant and native IFN-s, and clinical trials of native IFN-s. Weissman reported that human IFN-α has 14 different genes, three of which are known to be pseudogenes, and the other four are unclear. Mouse LFN-alpha clones have now been established. He believes that although IFN-α and IFN-β were differentiated four billion years ago, the differentiation of human and mouse IFN-α was about 700 million years ago. Goeddel has established four gene clones of calf IFN-alpha and E. coli (EC) and IFN-gamma clones of monkey cells. This gene is located in human 12th dyed