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目的探究络活喜与尼莫地平治疗老年人原发性高血压病的疗效及不良反应。方法选择我院老年人原发性高血压病患者110例随机分成两组各55例。络活喜组采用络活喜治疗;尼莫地平组采用尼莫地平治疗。比较两组患者原发性高血压病治疗效果。结果尼莫地平组患者的治疗总有效率比络活喜组高,P<0.05;两组患者治疗后舒张压、收缩压、LAEF和LAVI均显著降低,但络活喜组降低更明显,P<0.05;尼莫地平组不良反应发生率和络活喜组无显著差异,P>0.05。结论尼莫地平治疗老年人原发性高血压病的疗效优于络活喜,但各有侧重,尼莫地平可更好改善左室舒张功能,而络活喜可更好改善血压;两者不良反应轻微,安全性高。
Objective To investigate the efficacy and adverse reactions of loratadine and nimodipine in the treatment of elderly patients with essential hypertension. Methods 110 patients with essential hypertension in our hospital were randomly divided into two groups of 55 cases. Luohuoxue group treated with Luoxuetai; nimodipine group treated with nimodipine. Comparison of two groups of patients with primary hypertension treatment effect. Results The total effective rate of nimodipine group was higher than that of lovastatin group (P <0.05). After treatment, diastolic blood pressure, systolic blood pressure, LAEF and LAVI decreased significantly in both groups, <0.05. There was no significant difference in the incidence of adverse reactions between nimodipine and Luohuoxue (P> 0.05). Conclusion The efficacy of nimodipine in the treatment of essential hypertension in the elderly is better than that of lovastatin. However, nimodipine can improve left ventricular diastolic function better and lovox can improve blood pressure better; both Minor adverse reactions, high safety.