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观察了慢性支气管炎合并支气管哮喘、哮喘及慢性单纯型支气管炎的临床特点及发病机理。结果表明慢性支气管炎合并支气管哮喘与哮喘可有其它过敏性疾病及过敏性疾病家族史，发病前均有明显诱因，发作迅速，治疗需用肾上腺糖皮质激素；静脉血血栓素Ｂ２（ＴＸＢ２）均升高，６－酮－前列腺素Ｆ１．（６－ｋｅｔｏ－ＰＧＦ１ａ）均降低，西二醛（ＭＤＡ）均升高，两组均无显著差异（Ｐ＞０．０５），但均较慢性单纯型支气管炎有极显著差异（Ｐ＜０．０１）；静滴地塞米松１周后气通阻塞可逆性测定阳性率均明显高于慢性单纯型支气管炎，且有极显著差异（Ｐ＜０．０１）。
The clinical features and pathogenesis of chronic bronchitis complicated with bronchial asthma, asthma and chronic simple bronchitis were observed. The results showed that chronic bronchitis with bronchial asthma and asthma may have other allergic diseases and family history of allergic diseases, both before and after the onset of obvious incentives, rapid onset, the need for treatment of glucocorticoid glucocorticoid; venous thromboxane B2 (TXB2) were Elevated, 6-keto-prostaglandin F1. (6-keto-PGF1a) and the content of malondialdehyde (MDA) in both groups were significantly higher than those in chronic bronchitis (P <0.05) .01). The positive rate of air-through obstruction reversible test after intravenous dexamethasone 1 week was significantly higher than that of chronic simple bronchitis (P <0.01).