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目的：探讨食管癌术后颈部吻合口瘘入纵隔的预防、早期诊断和治疗方法。方法回顾性分析我院2010年3月~2012年7月食管癌颈部吻合术，术后发生颈部吻合口瘘入纵隔病例9例，总结其诊治经过。结果经保守治疗，8例治愈，死亡1例，死于感染性休克，致多器官功能衰竭。结论颈部吻合口瘘是食管癌术后的并发症，一般风险较小，但术后颈部吻合口瘘入纵隔，往往比胸内吻合口瘘风险更大，术后更难处理。所以早期诊断及选择适当的治疗方法能有效的提高吻合口瘘的治愈率。“,”Objective To investigate the prevention、early diagnosis and treatment of gastro esophageal anastomotic mediastinal fistula. Methods:The clinical data of patients undergoing esophageal resection combined with cervical anastomosis from March 2010 to June 2012 was retrospectively analyzed. 9 cases were diagnosed as gastroesophageal anastomotic mediastinal fistula. Results:8 cases were cured under conservative treatment. 1 case died with multiple organ failure. Conclusion:Cervical anastomic fistula is the complication after esophageal resection but with low risk. If the cervical anastomic mediastinal fistula formed, it was at great risk and not easy to cure. Early diagnose and proper therapy can improve the successful rate of the treatment.