Oxidative DNA damage in peripheral leukocytes and its association with expression and polymorphisms

• 作 者: TaoPeng Han-MingShen Zhi-MingL
• 机 构: DepartmentofHepatobiliarySugery,DepartmentofCommunity,DepartmentofGeneralSurgery,FusuiCancerResearch
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年10期
• 关键词: 外周血 白血球 DNA氧化损伤 基因多态性 肝细胞癌 青年人 高危因素
• 基金项目: 广西自然科学基金，广西教育厅科研项目，广西卫生厅医学基金，Singapore Science Grant

AIM: To study the oxidative DNA damage to adolescents of hepatocellular carcinoma (HCC) families in Guangxi Zhuang Autonomous Region, China.METHODS: Peripheral leukocytes' DNA 7, 8-dihydro-8-oxoguanine (8-oxoG) and repair enzyme hOGG1 were quantified