肠道病毒性脑膜炎患儿脑脊液中单核细胞增多与症状持续期间无关

• 作 者: Shah S.S. Hodinka R.L. Turnquist J.L. 贺莉
• 机 构: Division of Infectious Diseases Children's Hospital of Philadelphia North Campus 34th St. and Civic
• 出 处: 世界核心医学期刊文摘(儿科学分册)
• 发表日期: 2006年05期
• 关键词: 单核细胞增多 脑膜炎患儿 肠道病毒 脑脊液 症状 双变量回归模型 病毒性脑膜炎 百分数 白细胞 肠道

We used a binomial regression model to determine the relationship between the percent of cerebrospinal fluid (CSF)-mononuclear white blood cells and symptom duration in children with proven enteroviral meningitis. The odds of a CSF white blood cell being mononuclear increased by 15.7%(95%confidence interval: -3.8%to 38.0%; P = .11) for each day of symptoms. Fifty percent of patients with symptoms of 1 day or less had predominance of mononuclear cells among CSF white blood cells. These findings suggest that factors other than symptom duration influence the composition and evolution of the CSF white blood cell response to enteroviral infection.

We used a binomial regression model to determine the relationship between the percent of cerebrospinal fluid (CSF) -mononuclear white blood cells and symptom duration in children with proven enteroviral meningitis. The odds of a CSF white blood cell being mononuclear increased by 15.7% (95 % confidence interval: -3.8% to 38.0%; P = .11) for each day of symptoms. Fifty percent of patients with symptoms of 1 day or less had predominance of mononuclear cells among CSF white blood cells. These findings suggest that factors other than symptom duration influence the composition and evolution of the CSF white blood cell response to enteroviral infection.