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男性泌催乳素垂体瘤可引起性机能减退、阳萎和不育症;若瘤体过大尚可引起视野缺损或脑神经麻痹等局部症状或体征。手术疗法,甚至联合放射治疗的效果并不满意,许多病人需再次手术,而且治疗后仍有高催乳素血症。本文报道用溴隐亭治疗可使肿瘤消退,并抑制血内催乳素浓度。研究对象为8例男性高催乳素血症患者,年龄25~64岁,病程4年以上。全部患者给予溴隐亭20mg/d,治疗3~11个月。结果原7例阳萎患者经治疗后5例恢复正常、1例改善;3例头或面部疼痛患者全部得到缓解。治疗前7例进行 CT 扫描检查均证实垂体肿瘤的患者,治疗后再次检查证实瘤体缩小,4例蝶鞍变为部分或
Male secretion of prolactin pituitary tumor can cause sexual dysfunction, impotence and infertility; if the tumor is too large can still cause visual field defects or cranial nerve paralysis and other local symptoms or signs. Surgery, and even combined radiotherapy are not satisfactory, many patients need reoperation, and there is still hyperprolactinemia after treatment. This article reports that treatment with bromocriptine regresses tumors and inhibits prolactin concentrations in the blood. The subjects were 8 male patients with hyperprolactinemia, aged 25 to 64 years, duration of 4 years or more. All patients were given bromocriptine 20mg / d for 3 to 11 months. Results The original 7 cases of impotence patients returned to normal after treatment, 1 case improved; 3 patients with head or facial pain were all alleviated. 7 cases before treatment for CT scan examination confirmed pituitary tumor patients, after treatment, re-examination confirmed the tumor narrowed, 4 cases of sella turned into partial or