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非化学因素、非辐射因素发生的急性出血性膀胱炎(Acute Hemorrhagic Cystitis,AHC)过去称为膀胱紫癜症、非细菌性AHC、特发性AHC。病因不明,有植物神经功能失调、变态反应、支原体感染、病毒感染等假说。1966年熊坂从2例患者尿中分离出11型腺病毒(Ad_(11)),血清中和抗体升高,首次确定了Ad_(11)与AHC的病原联系。后进一步得到证实。目前认为腺病毒AHC是一种独立的疾病实体。
Acute Hemorrhagic Cystitis (AHC), a non-chemisorning, nonradiative factor, was formerly known as Bladder Purpura, Non-Bacterial AHC, and Idiopathic AHC. Etiology is unknown, with autonomic dysfunction, allergic reaction, mycoplasma infection, viral infection and other hypotheses. In 1966, Kuzaka isolated the type 11 adenovirus (Ad_ (11)) from the urine of two patients and the serum neutralizing antibody was elevated. For the first time, the pathogen connection between Ad_ (11) and AHC was confirmed. After further confirmed. AHC is currently considered an independent disease entity.