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骨质疏松是许多健康成年人均可 患的一种常见疾病,预防骨折的对策包括最佳的峰值骨密度及预防因绝经和随着年龄增长而引起的骨质丢失。遗传基因营养和生活方式是影响峰值骨密度的因素,也是预防的重点,一旦达到峰值骨密度,骨的吸收增加可能是主要的发病因素。目前,治疗骨质疏松的主要药物有:钙加维生素D、雌激素替代治疗、降钙素及etidronate,它们可以抑制骨的吸收。骨的生成少于骨的吸收也可造成骨质丢失,氟化物及间歇的甲状旁腺激素治疗可以增加骨的生成,然而其确切疗效还有待于进一步论证,胰岛
Osteoporosis is a common disease that many healthy adults can tolerate. Measures to prevent fractures include optimal peak bone density and prevention of bone loss due to menopause and age. Genetics and lifestyle are the factors that influence peak BMD and are the focus of prevention. Once peak BMD is reached, increased bone resorption may be the primary risk factor. At present, the main drugs for the treatment of osteoporosis are: calcium and vitamin D, estrogen replacement therapy, calcitonin and etidronate, they can inhibit bone resorption. Bone formation less than the absorption of bone can also cause bone loss, fluoride and intermittent parathyroid hormone therapy can increase the formation of bone, however, its exact efficacy remains to be further demonstrated that islets