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目的:探讨有非离子造影剂过敏史的患者接受经皮冠状动脉介入治疗(PCI)的安全性和术前预防性抗过敏治疗的效果。方法:参考相关文献资料,分析典型病例的处理方法。结果:经术前预防性抗过敏治疗,患者PCI术中未发生过敏反应,术后第3天发生轻度迟发性过敏反应,经口服H1受体阻断剂后好转,安全出院。结论:有非离子造影剂过敏史的患者在PCI术中再次接触造影剂有较大过敏风险,预防性应用糖皮质激素可降低再过敏几率,但仍可能发生再过敏。
Objective: To investigate the safety of percutaneous coronary intervention (PCI) and the effect of preoperative prophylactic antiallergic treatment in patients with a history of allergy to nonionic contrast agents. Methods: With reference to relevant literature, analyze the treatment of typical cases. Results: Preoperative prophylactic antiallergic treatment did not cause any allergic reaction during PCI. Mild delayed hypersensitivity reaction occurred on the 3rd postoperative day. After oral administration of H1 receptor antagonist, it improved and was discharged safely. CONCLUSIONS: Patients with a history of non-ionic contrast media allergies have a greater risk of allergic contact with contrast media during PCI. Prophylactic glucocorticoid therapy may reduce the risk of re-allergy but may still cause re-allergy.