【摘 要】
:
目的:观察黄连紫草膏联合重组人表皮生长因子(rhEGF)凝胶局部应用治疗小面积深Ⅱ度烧伤创面的效果及对患者疼痛程度和创面细菌感染的影响.方法:选取河南省鹤壁市人民医院急诊科2018年7月—2020年11月收治的89例小面积深Ⅱ度烧伤患者作为研究对象,创面面积4%~11%TBSA.采用抽签法将患者分为两组.对照组44例给予rhEGF凝胶创面涂抹治疗,观察组45例创面依次涂抹黄连紫草膏和rhEGF凝胶,比较两组患者治疗4周后的临床疗效、创面愈合时间,以视觉模拟评分法(VAS评分)对治疗后1、7、14、21 d
【机 构】
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河南省鹤壁市人民医院急诊科,河南 鹤壁 458030;河南省鹤壁市人民医院肾内风湿科,河南 鹤壁 458030
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目的:观察黄连紫草膏联合重组人表皮生长因子(rhEGF)凝胶局部应用治疗小面积深Ⅱ度烧伤创面的效果及对患者疼痛程度和创面细菌感染的影响.方法:选取河南省鹤壁市人民医院急诊科2018年7月—2020年11月收治的89例小面积深Ⅱ度烧伤患者作为研究对象,创面面积4%~11%TBSA.采用抽签法将患者分为两组.对照组44例给予rhEGF凝胶创面涂抹治疗,观察组45例创面依次涂抹黄连紫草膏和rhEGF凝胶,比较两组患者治疗4周后的临床疗效、创面愈合时间,以视觉模拟评分法(VAS评分)对治疗后1、7、14、21 d换药时疼痛程度进行评估,采用简明烧伤健康量表(BSHS-B)评分评估患者的生活质量,比较伤后1、7、14、21 d的创面细菌培养情况.结果:观察组治疗4周后总有效率(82.22%)较对照组的(61.36%)高(P<0.05).观察组创面愈合时间快于对照组[(16.37±1.54)d比(21.85±2.11)d,P0.05);治疗后两组评分均较治疗前升高,观察组高于对照组(P0.05),随后评分逐渐下降,观察组下降更为明显,治疗第7、14、21天的VAS评分均明显低于对照组(P0.05).结论:黄连紫草膏联合rhEGF凝胶局部治疗可减轻患者换药疼痛,促进创面愈合,提高生活质量,且黄连紫草膏并不增加创面感染风险.
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