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目的探讨肝动脉门静脉双介入化疗栓塞方法治疗原发性肝癌的可行性及临床应用。方法28例原发性肝癌患者均行超声引导下经皮穿肝至门脉造影同时行股动脉穿刺肝动脉置管造影。依据肿瘤所属肝动脉、门静脉分支的范围,数目及血流情况选择适当化疗药物和栓塞剂进行治疗。结果手术后1个月复查肿瘤均有不同程度缩小,碘油沉积大部分良好。4例患者正准备接受二期手术切除。无严重并发症出现。8例患者术后1周出现一过性肝功能异常,经保肝治疗2周后好转。结论肝动脉门静脉双介入化疗栓塞治疗原发性肝癌是安全有效的方法。
Objective To investigate the feasibility and clinical application of hepatic arterial portal vein dual interventional chemotherapy and embolization in the treatment of primary liver cancer. Methods Twenty-eight patients with primary liver cancer underwent percutaneous transhepatic hepatic arterial angiography with ultrasound-guided percutaneous transhepatic arterial catheterization. According to the tumor belongs to the hepatic artery, portal vein branch of the range, the number and blood flow to select the appropriate chemotherapy drugs and embolic agents for treatment. Results One month after surgery, the tumor size was reduced to varying degrees, most of the lipiodol deposition was good. Four patients are preparing to undergo two surgical resections. No serious complications appear. One patient had abnormal liver function one week after operation in 8 patients, which improved after 2 weeks of treatment. Conclusions Hepatic artery portal vein double-intervention chemotherapy for primary liver cancer is a safe and effective method.