论文部分内容阅读
目的通过对伊曲康唑注射液治疗ICU中侵袭性肺部真菌感染的研究评价其疗效。方法选择2009年1月至2009年11月大连医科大学附属第一医院ICU侵袭性肺部真菌感染患者19例,应用伊曲康唑进行治疗。结果 19例患者共检出真菌菌株57株,其中热带念珠菌占首位23株,其次为白色念珠菌15株,光滑假丝酵母菌8株,克柔念珠菌6株,曲霉菌5株。在接受治疗的患者中痊愈14例,显效2例,好转1例,死亡2例,总有效率84.2%。结论伊曲康唑注射液是治疗侵袭性肺部真菌感染有效的药物,临床上可作为一线用药治疗使用。
Objective To evaluate the efficacy of itraconazole injection in the treatment of invasive pulmonary fungal infection in the ICU. Methods From January 2009 to November 2009, 19 patients with ICU-invasive pulmonary fungal infection in the First Affiliated Hospital of Dalian Medical University were treated with itraconazole. Results Totally 57 fungal strains were detected in 19 patients, of which 23 were Candida tropicalis, followed by 15 Candida albicans, 8 Candida glabrata, 6 Candida krusei and 5 Aspergillus. In the treatment of patients recovered in 14 cases, 2 cases markedly improved in 1 case, 2 patients died, the total efficiency of 84.2%. Conclusion Itraconazole injection is an effective drug for the treatment of invasive pulmonary fungal infection and can be used clinically as first-line therapy.