论文部分内容阅读
[目的]观察醒脾养儿颗粒联合甘草锌治疗小儿轮状病毒肠炎(RVE)的临床疗效和安全性。[方法]将102例RVE患儿随机分为观察组(n=51)与对照组(n=51)。2组均予蒙脱石散、微生态制剂、补液及指导饮食等治疗。对照组口服甘草锌颗粒按元素锌计算,用量0.5~1.5mg/(kg·d),3次/d,口服。观察组在对照组基础上加用醒脾养儿颗粒,<1岁:2g/次,2次/d;1~2岁:4g/次,2次/d;≥3岁:4g/次,3次/d。一疗程为5d。观察对比治疗结果。[结果]临床总有效率对照组70.59%,观察组98.04%,2组比较差异有统计学意义(P<0.01);观察组腹泻消失时间明显短于对照组(P<0.01);治疗后观察组大便轮状病毒抗原转阴率明显高于对照组(P<0.01)。[结论]醒脾养儿颗粒联合甘草锌治疗小儿RVE能有效改善患儿的临床症状,缩短疗程,未见明显不良反应。
[Objective] To observe the clinical efficacy and safety of “Xing - Pi Yang Er Granule” and “Liquorice Zinc” in treating children rotavirus enteritis (RVE). [Methods] 102 children with RVE were randomly divided into observation group (n = 51) and control group (n = 51). The two groups were treated with montmorillonite powder, probiotics, rehydration and diet guidance. The control group of oral zinc licorice particles calculated by elemental zinc, the amount of 0.5 ~ 1.5mg / (kg · d), 3 times / d, orally. The observation group was added with Xingnao granule on the basis of the control group, <1year: 2g / time, 2times / d; 1 ~ 2years: 4g / time, 2times / d; Times / d. A course of treatment for 5d. Observation and comparison of treatment results. [Results] The total clinical effective rate was 70.59% in the control group and 98.04% in the observation group, with significant difference between the two groups (P <0.01). The disappearance time of the diarrhea in the observation group was significantly shorter than that in the control group (P <0.01) Group stool virus rotavirus negative rate was significantly higher than the control group (P <0.01). [Conclusion] Xingpi Yangling granule combined with zinc glycyrrhizinate can effectively improve the clinical symptoms, shorten the course of treatment in children, and no obvious adverse reactions.