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1 资料与方法 1.1 一般资料 106名住院患儿均符合全国病毒性肝炎防治座谈会上制定的婴儿肝炎综合征诊断标准,平均年龄1~7月,男64例,女42例,均有高胆红素血症,ALT异常,伴有消化道症状,部分伴有呼吸道症状。 1.2 方法 1.2.1 血清学检测:全部病例母婴均作尿巨细胞病毒(CMV)分离,血清CMV-IgM及乙肝病毒(HBV)标志物检测,部分病例检测血清抗HCV、抗HEV-IgM。 1.2.2 肝脏、胆囊、脾脏动态B超观察。 1.2.3 手术治疗时所见组织病理改变。
1 Materials and Methods 1.1 General Information 106 hospitalized children are in line with the National Syndrome of hepatitis prevention and treatment developed at the symptomatic diagnosis of infant hepatitis syndrome, the average age of 1 to 7 months, 64 males and 42 females, Hyalinemia, ALT abnormalities, associated with gastrointestinal symptoms, some accompanied by respiratory symptoms. 1.2 Methods 1.2.1 serological test: all cases of mother and child were urine cytomegalovirus (CMV) separation, serum CMV-IgM and hepatitis B virus (HBV) markers detection, some cases of serum anti-HCV, anti-HEV-IgM. 1.2.2 liver, gallbladder, spleen dynamic B-observation. 1.2.3 surgical treatment of histopathological changes seen.