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近几年来，对消化性溃疡的发病机制、新药研制、药物治疗等的研究，都取得了引人注目的进展。现综述如下：一、消化性溃疡的病因及治疗药物概况消化性溃疡（简称溃疡）的病因和发病机制较复杂，至今尚未阐明，现已提出的理论和假设有：1．无酸即无溃疡。这句名言是Schwarz氏于1910年提出的。在此理论指导下研制了大批制酸剂，诸如碳酸氢钠、氢氧化铝凝胶、钙铋镁等。目前仅对这类药的剂型和用药方案作了进一步的改善。2．平衡理论。现代医学认为胃酸（攻击因子）分泌过度和/或胃肠粘膜防御体系削弱（即平衡失调）是引起溃疡的基本原因。在此理论指导下研制了一系列抑制胃酸分泌的药物和增强粘膜防御因子的药物，从而革新了溃疡病的治疗，并取得了卓越成就。
In recent years, the pathogenesis of peptic ulcer, new drug development, drug treatment research, have made remarkable progress. Are summarized as follows: First, the etiology and treatment of peptic ulcer peptic ulcer peptic ulcer (etiology and pathogenesis of the more complicated, has not yet been clarified, the theory has been put forward and hypotheses are: 1. No acid or ulcer. This famous quote was made by Schwarz in 1910. Under the guidance of this theory, a large number of antacids have been developed, such as sodium bicarbonate, aluminum hydroxide gel, calcium magnesium bismuth and the like. At present, only the formulation and dosage regimen of such drugs have been further improved. 2. Balance theory. Modern medicine has suggested that excessive secretion of gastric acid (attacker) and / or impaired gastrointestinal mucosal defense (ie, imbalanced) are the underlying causes of ulcers. Under the guidance of this theory, a series of drugs that inhibit gastric acid secretion and drugs that enhance mucosal defensive factors have been developed, which has revolutionized the treatment of ulcer disease and achieved remarkable achievements.