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目的探讨检测血清N末端B型钠尿肽原(NT-pro BNP)和心脏型脂肪酸结合蛋白(h-FABP)水平对妊娠期糖尿病(GDM)患者早期心肌损害的监测价值。方法选择我院住院和门诊临床确诊的GDM患者120例,并选择同期正常妊娠期妇女120例作为对照组。检测各组血清中NT-pro BNP和h-FABP水平,并进行对比分析。结果 GDM患者血清NT-pro BNP和h-FABP水平高于对照组,差异有统计学意义(P<0.01)。结论联合检测血清NT-pro BNP及h-FABP水平可及时了解GDM患者早期心肌细胞损害及心脏功能情况,对指导治疗及改善预后具有重要意义。
Objective To investigate the value of serum NT-proBNP and h-FABP in detecting early myocardial damage in patients with gestational diabetes mellitus (GDM). Methods 120 cases of GDM patients hospitalized in our hospital and clinically diagnosed in our hospital were selected and 120 normal pregnant women were selected as the control group. The serum levels of NT-pro BNP and h-FABP in each group were detected and compared. Results The serum levels of NT-pro BNP and h-FABP in GDM patients were significantly higher than those in control group (P <0.01). Conclusions The combined detection of serum NT-pro BNP and h-FABP levels can keep early understanding of cardiac myocyte damage and cardiac function in GDM patients, which is of great significance for guiding treatment and improving prognosis.