论文部分内容阅读
目的探讨观察瑞舒伐他汀钙强化治疗对冠脉小血管病变和临界病变患者的临床治疗效果。方法选择2010年5月~2015年5月在我院心血管内科行冠脉造影检查,结果提示为小血管病变或临界病变且无介入手术治疗指证的患者60例。随机分为强化组和常规组,每组各30例。两组患者治疗6个月后复查冠状造影,比较两组冠脉狭窄程度。结果(1)强化组继续狭窄率为3.33%,常规组继续狭窄率为13.33%,两组比较有统计学差异(P﹤0.05)。(2)两组血脂水平均有下降,两组比较有统计学差异(P﹤0.05),且强化组LDL-C下降更明显。结论瑞舒伐他汀钙强化治疗对冠脉小血管病变和临界病变血管的继续狭窄有抑制作用。
Objective To investigate the clinical effect of rosuvastatin calcium fortification on patients with coronary artery disease and critical lesion. Methods From May 2010 to May 2015 in our hospital cardiovascular surgery coronary angiography, the results suggest that small vessel lesions or critical lesions without interventional surgery in patients with indications of 60 cases. Randomly divided into intensive group and conventional group, 30 cases in each group. Coronary angiography was performed in both groups 6 months after treatment, and the degree of coronary stenosis was compared between the two groups. Results (1) The stenosis rate was 3.33% in the intensive group and 13.33% in the conventional group. There was significant difference between the two groups (P <0.05). (2) The level of blood lipid decreased in both groups, there was significant difference between the two groups (P <0.05), and the decrease of LDL-C in intensive group was more obvious. Conclusions Rosuvastatin calcium therapy has an inhibitory effect on coronary artery stenosis and critical stenosis.