Chip-based visual detection of microRNA using DNA-functionalized gold nanoparticles

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：liongliong523

【摘要】

：

在现在的学习，我们开发了由探针和基因削检测 microRNAs (miRNAs ) 的金 nanoparticle (AuNP ) 组成的一个高度敏感、方便的生物传感器。特定的 oligonucleotides 为目标 miRN

【作者】

：

Ping Wang Jianlong Zhao Bin Hu

【机构】

：

TheMolecularMedicineKeyLaboratoryofLiverInjuryandRepair,StateKeyLaboratoryofTransducerTechnology,Cli

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2016年5期

【关键词】

：

MICRORNA 金纳米粒子视觉检测芯片检测官能化 DNA miRNA 探针杂交 microRNA gold nanoparticles chip

【基金项目】

：

Acknowledgements This work was supported by the National Basic Research Program of China （2012CB933303）, the National Natural Science Foundation of China （61571429, 61571077, 61401442）, the Innova- ti

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在现在的学习，我们开发了由探针和基因削检测 microRNAs (miRNAs ) 的金 nanoparticle (AuNP ) 组成的一个高度敏感、方便的生物传感器。特定的 oligonucleotides 为目标 miRNAs 作为俘获探针被纳入玻璃表面，它然后经由杂交被检测到 AuNP 探针。信号被 H 24 的减小放大 > O 2 。一根单个

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Chip-based visual detection of microRNA using DNA-functionalized gold nanoparticles

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