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目的 总结糖尿病患者血脂异常的规律 ,分析血脂异常与某些慢性并发症的关系。方法 建立计算机管理糖尿病资料库 ,血脂测定及并发症筛查。结果 2 5 4 5例糖尿病患者中 ,血脂 4项正常组 882例 ,占 35 0 % ;血脂异常16 6 3例 ,占 6 5 0 % ,其中总胆固醇 (TC)和甘油三酯 (TG)都升高者占 2 2 8%。高血压检出率正常组 39 2 % ,血脂异常组4 8 3% ,其中高TC和高TG组高达 5 3 2 %。大血管病变的检出率与血脂正常组 (2 4 0 % )比较 ,高TC高TG组为33 6 % ,P <0 0 1。肾脏病变检出率血脂正常组为 2 3 2 % ,高TC组为 2 9 3% ,P <0 0 5 ;高TC高TG组为 30 6 % ,P <0 0 1。高TC组黄斑病变检出率较高 ,为 10 2 % (P <0 0 5 )。神经病变的检出率在血脂异常各组与血脂正常组均无显著性差别。结论 本组糖尿病患者血脂异常的发生率高达 6 5 % ,血脂异常以TC和TG均升高较多。高血压的检出率与血脂异常有一定相关性 ,舒张压升高更明显
Objective To summarize the regularity of dyslipidemia in diabetic patients and analyze the relationship between dyslipidemia and some chronic complications. Methods To establish a database of computerized management of diabetes, blood lipid determination and complication screening. Results Among 25 54 diabetic patients, 882 were normal in 4 groups, accounting for 35.0% of the total, and 16 63 were dyslipidemia, accounting for 65.0%. Among them, total cholesterol (TC) and triglyceride The rise accounted for 22.8%. The prevalence of hypertension was 39.2% in the normal group and 48.3% in the dyslipidemia group, with 53.2% in the high TC group and the high TG group. The detection rate of macrovascular disease was 33.6% (P <0.01) in the high TC high TG group compared with the normal blood lipid group (240%). The detection rate of renal disease was 23.2% in the normal blood lipids group, 29.3% in the high TC group, P <0 05, and 30 6% in the high TC high TG group (P <0.01). The detection rate of maculopathy in high TC group was higher (102%, P <0 05). The detection rate of neuropathy in each group of dyslipidemia and normal blood lipids were no significant difference. Conclusion The incidence of dyslipidemia in patients with diabetes mellitus in this group is as high as 65%. The levels of TC and TG in dyslipidemia are both higher. The detection rate of hypertension and dyslipidemia have a certain correlation, diastolic blood pressure increased more significantly