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目的:通过对我院临床抗生素应用情况的调查分析,了解我院实行处方限价前后抗生素应用的现状、评价其合理性,分析临床不合理使用抗生素的原因。方法:随机抽取我院2007年1月至2007年12月的门诊处方,1d/周,统计抗生素的使用频度、药品总消耗量、约定日剂量和药物利用指数。结果:处方限价能够对抗生素的滥用起到一定的抑制作用。结论:我院临床抗生素的使用存在整体上起点高,档次高的问题,头孢菌素类在我院抗生素应用中占主导地位,一些在临床应用多年、疗效确切、价格便宜的抗生素品种被新药代替,使用量逐渐下降。分析结果表明,临床抗生素的合理应用问题不容忽视,必须引起医药界乃至全社会的重视。
Objective: To investigate the clinical application of antibiotics in our hospital to understand the situation before and after the implementation of prescription antibiotics in our hospital, to evaluate the rationality of antibiotics to analyze the reasons for unreasonable use of clinical. Methods: Outpatient prescriptions were randomly selected from January 2007 to December 2007 in our hospital for 1d / week. The frequency of antibiotic use, total drug consumption, contracted daily dosage and drug utilization index were calculated. RESULTS: The prescription limit could have some inhibitory effect on the abuse of antibiotics. Conclusion: The use of antibiotics in our hospital has the problem of high starting point and high grade as a whole. Cephalosporins dominate the application of antibiotics in our hospital. Some of them are used clinically for many years with definite curative effect and cheap antibiotic varieties replaced by new drugs , The use of gradually decreased. Analysis results show that the rational application of clinical antibiotics can not be ignored, must draw the attention of the pharmaceutical industry and the whole society.