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In this paper, adaptive genetic algorithm (AGA) is applied to topology optimization of truss structure with frequency domain excitations. The optimization constraints include fundamental frequency, displacement responses under force excitations and acceleration responses under foundation acceleration excitations. The roulette wheel selection operator, adaptive crossover and mutation operators are used as genetic operators. Some heuristic strategies are put forward to direct the deletion of the extra bars and nodes on truss structures. Three examples demonstrate that the proposed method can yield the optimum structure form and the lightest weight of the given ground structure while satisfying dynamic response constraints.