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目的探讨慢性肾脏病患者急性肾损伤的致病因素及临床治疗要点。方法回顾本院收治、并发急性肾损伤的98例慢性肾脏病患者,对其发病原因、临床治疗疗效和预后做综合分析。结果 C/A的发病与年龄密切相关,多发于老年人,98例患者中,年龄>60岁患者占70.4%(69例);且不同年龄段患者的诱发因差异有统计学意义(P<0.05),老年人的诱发因主要是感染、心血管疾病和药物,而青壮年则以原发病进展为主要因素;高发C/A的基础性肾病主要是高血压肾病、糖尿病肾病及肾小球肾炎。结论 C/A的致病因在不同年龄段有不同的侧重点,可做针对性预防;准确寻找致病因和及时对症治疗是提高临床疗效的关键。
Objective To explore the pathogenesis of acute kidney injury in patients with chronic kidney disease and clinical treatment. Methods A retrospective review of 98 patients with chronic kidney disease admitted to our hospital and complicated with acute renal injury and analyzed their causes, clinical effects and prognosis. Results The incidence of C / A was closely related to age and was mainly in the elderly. Of the 98 patients, 70.4% (69 cases) were older than 60 years old. The incidence of C / A was significantly different between different age groups (P < 0.05). The predisposing causes of the elderly were mainly infections, cardiovascular diseases and drugs, while the young and middle-aged patients were the primary factors for the progression of the primary disease. The primary renal diseases with high incidence of C / A were hypertensive nephropathy, diabetic nephropathy and kidney disease Ball nephritis. Conclusion The cause of C / A has different emphasis in different age groups and can be targeted prevention. Accurately looking for the cause of disease and timely symptomatic treatment are the keys to improve clinical efficacy.