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目的探讨同型半胱氨酸与冠心病的关系。方法选择80例符合冠心病诊断标准的患者,分析冠动脉狭窄程度、年龄、性别及不同类型冠心病之间同型半胱氨酸的表达,并与正常健康人做比较。结果同型半胱氨酸含量男性高于女性,冠心病组高于正常组,冠动脉狭窄程度越高同型半胱氨酸含量越高。结论同型半胱氨酸不仅可能与冠心病的发生、发展有直接关系,而且可能是促使急性冠脉病变发生的重要因素。同型半胱氨酸与冠心病具有密切联系,检测血浆同型半胱氨酸水平对于冠心病的预防、诊断和治疗具有一定的临床价值。
Objective To investigate the relationship between homocysteine and coronary heart disease. Methods Eighty patients who met the diagnostic criteria of coronary heart disease were selected to analyze the degree of coronary artery stenosis, age, gender and the homocysteine expression between different types of coronary heart disease and to compare with normal healthy people. Results The content of homocysteine was higher in males than in females, coronary heart disease was higher than that in normal subjects, and the content of homocysteine was higher in patients with coronary artery stenosis. Conclusion Homocysteine may not only have a direct relationship with the occurrence and development of coronary heart disease, but also be an important factor to promote acute coronary artery disease. Homocysteine and coronary heart disease are closely linked to detect plasma homocysteine levels for the prevention, diagnosis and treatment of coronary heart disease has a certain clinical value.