Total saponins in Rubus parvifolius L.induce lymphoma cells apoptosis through upregulated Bax/Fas an

• 作 者: Xiao-Feng Xu Ru-Bin Cheng Xue-
• 机 构: DepartmentofHematology,CollegeofPharmaceuticalScience,TheFirstAffiliatedHospital
• 出 处: TMR传统医学研究
• 发表日期: 2019年2期
• 关键词: Total SAPONINS of RUBUS parvifolius L. BCL-2 BAX FAS APOPTOSIS Lymphoma
• 基金项目: grants from Zhejiang Provincial Administration of Traditional Chinese Medicine (No.2011ZA081,2013ZB095 and 2015ZA147),Hangzhou Medical Science and Technology Plan (No.2012A048).

Purpose:To investigate the effect of total saponins of Rubus parvifolius L.(TSRP)on lymphoma Raji cells and further discuss its mechanism.Methods:The model of nude mice bearing Raji cells was established,the volume,weight and inhibition rate of the transp