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[目的]观察中药柴芍承气汤联合活血化瘀药物丹红注射液治疗重症急性胰腺炎(severe acute pancreatitis,SAP)的临床疗效。[方法]将80例SAP患者分为对照组(n=40)和治疗组(n=40)。对照组给予单纯常规治疗,如:抑制胰腺分泌,降低胰管内压,减少胰液外渗,抗感染;治疗组在常规治疗的同时加用中药柴芍承气汤和丹红注射液。观察2组患者腹痛缓解、消失时间、血淀粉酶恢复正常时间以及住院时间和临床总有效率。[结果]治疗组患者腹痛缓解、消失时间以及血淀粉酶恢复正常时间均短于对照组(P<0.05),且临床总有效率明显优于对照组(P<0.05)。[结论]中药柴芍承气汤联合丹红治疗可以显著的改善SAP患者各项临床观察指标,缩短住院时间,提高临床疗效。
[Objective] To observe the clinical effect of traditional Chinese medicine Chaishao Chengqi Decoction combined with Danhong injection for promoting blood circulation and removing blood stasis to treat severe acute pancreatitis (SAP). [Methods] Eighty SAP patients were divided into control group (n = 40) and treatment group (n = 40). The control group were given simple routine treatment, such as: inhibition of pancreatic secretion, reduce pancreatic duct pressure, reduce pancreatic fluid extravasation, anti-infection; the treatment group in the conventional treatment at the same time with traditional Chinese medicine Chaishao Chengqi Decoction and Danhong injection. Abdominal pain relief, disappearance time, blood amylase recovery time and hospitalization time and total clinical efficiency were observed in two groups. [Results] The pain relief, disappearance time and the recovery time of blood amylase in the treatment group were shorter than those in the control group (P <0.05), and the total clinical effective rate was significantly better than that in the control group (P <0.05). [Conclusion] The treatment of traditional Chinese medicine Chaishaochengqi Decoction combined with Danhong can significantly improve various clinical observation indexes of SAP patients, shorten the length of hospital stay and improve the clinical curative effect.