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从草乌——北乌头(Aconitum kusnezoffii Reichb.)的块根——中分离得到16个单体成分,据波谱方法分别鉴定为:乌头碱(aconitine,1)、3-脱氧乌头碱(3-deoxyaconitine,2)、中乌头碱(mesaconitine,3)北乌碱(beiwutine,4)、次乌头碱(hypaconitine,5)、10-羟基乌头碱(aconifine,6)、14-苯甲酰乌头原碱(14-benzoylaconine,7)、14-苯甲酰中乌头原碱(14-benzoylmesaconine,8)、尼奥宁(neoline,9)、15-α-羟基尼奥宁(15-α-hydroxyneoline,10)、查斯曼宁(chasmanine,11)、塔拉萨敏(talatizamine,12)、弗斯生(foresticine,13)、牛扁碱(lycoctonine,14)、氨茴酰牛扁碱(anthranoyllycoctonine,15)和一海替生重排产物16。其中化合物6～16为首次从该植物中分得。
Sixteen monomer components were isolated from the tuberous roots of Aconitum kusnezoffii Reichb. According to spectral methods, they were identified as aconitine (1), 3-deoxyaconitine 3-deoxyaconitine, 2) mesaconitine, beiwutine, hypaconitine, aconifine, 14-benzoylaconine (7), 14-benzoylmesaconine (8), neoline (9) and 15-alpha-hydroxynionine Alpha-hydroxyneoline, 10), chasmanine (11), talatizamine (12), foresticine (13), lycoctonine (14) Anthranoyllycoctonine (15) and a melanin 16. Compounds 6-16 were isolated from this plant for the first time.