论文部分内容阅读
目的探讨耐甲氧西林金黄色葡萄球菌院内流行、感染、爆发控制相关因素,以提高医院感染控制水平。方法回顾分析我院2003～2008年MRSA检出率、感染分布、耐药、ICU隔离控制效果进行对照分析。结果①MRSA感染率逐年增高,MRSA院内感染爆发次数亦逐年增高;②采取隔离措施后,ICU科MRSA检出株数明显下降,前后比较差异显著(χ2=24.28,P<0.01);③MRSA对万古霉素、替考拉宁和利奈唑胺的耐药率为0%。结论万古霉素、替考拉宁和利奈唑胺是治疗MRSA感染首选药物;MRSA感染病例数逐年增高,并随院内感染爆发次数的增加而递增;集中MRSA患者和隔离措施是有效地控制MRSA爆发感染关键。
Objective To investigate the epidemic, infection and outbreak control factors of methicillin-resistant Staphylococcus aureus in order to improve the level of nosocomial infection control. Methods Retrospective analysis of our hospital from 2003 to 2008 MRSA detection rate, infection distribution, drug resistance, ICU isolation control effect of controlled analysis. Results ① The infection rate of MRSA increased year by year, and the number of nosocomial infections in MRSA also increased year by year. ② After isolation, the number of MRSA strains in ICU Section decreased significantly (χ2 = 24.28, P <0.01) , Teicoplanin and linezolid resistance rate was 0%. CONCLUSION: Vancomycin, teicoplanin and linezolid are the first choice for the treatment of MRSA. The number of MRSA infections increases year by year and increases with the number of nosocomial infections. Concentration of MRSA patients and isolation measures are effective in controlling MRSA outbreak The key to infection.