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目的 :研究不同时间点华北食管癌高发区危险因素的变化情况 ,为监测提供依据。方法 :以同一地区不同时间断面 (1985年、1991年和 1997年 )人群为基础的病例对照研究作为研究对象。使用条件和非条件 L ogistic模型分析和 Spearman相关分析。结果 :肉类、蔬菜和饮酒的比例随时间推移而增加 ,酸菜比例下降。 1985年、1991年和 1997年男性吸烟 OR值分别为 0 .9、1.8和 1.0。食管癌家族史 1.7、1.4和 1.9。体型指数 1991年和 1997年为 0 .9、0 .8、0 .7和 0 .4、0 .3、0 .2。按食用频率分层 ,肉类 1.6、1.5、1.0、1.0和 1.2、1.7;新鲜蔬菜 1.5、1.5、1.0、0 .8和 0 .8、0 .7;玉米 1985年、1997年为 1.4、1.3、1.5和 1.0、0 .8、0 .6。结论 :经济条件可以影响食管癌危险因素如饮酒、酸菜等。饮酒可能成为新的危险因素。
Objective: To study the changes of risk factors of high incidence of esophageal cancer in North China at different time points and provide evidence for monitoring. METHODS: A case-control study based on population-based cross-sections (1985, 1991 and 1997) in the same area was used as the study object. Conditions of use and unconditional L ogistic model analysis and Spearman correlation analysis. Results: The proportion of meat, vegetables and alcohol increased over time and the proportion of sauerkraut decreased. In 1985, 1991 and 1997, male smoking OR values were 0.9, 1.8 and 1.0 respectively. Family history of esophageal cancer 1.7, 1.4 and 1.9. Body type index in 1991 and 1997 were 0.9, 0.8, 0.7 and 0.4, 0.3, 0.2. Stratified according to the edible frequency, meat 1.6, 1.5, 1.0, 1.0 and 1.2, 1.7; fresh vegetables 1.5, 1.5, 1.0, 0.8 and 0.8, 0.7; maize 1985, , 1.5 and 1.0,0 .8,0 .6. Conclusion: Economic conditions can affect esophageal cancer risk factors such as drinking, pickled cabbage and so on. Alcohol consumption may be a new risk factor.