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ZES累及食管者甚为罕见。最初认为这与胃泌素可使下端食管括约肌压力及平滑肌张力增加,从而防止胃-食管反流有关,但随后许多作者予以否定。本文复习了18例ZES的食管病变。材料与方法:作者从1962年～1983年30例临床上疑为ZES的病例中筛选出有完整资料并经病理证实的18例作了回顾性分析。4例于诊断ZES之前6个月至3年有心窝烧灼感和吞咽困难。包括1例因溃疡病作过部份胃切除和胃空肠吻合术,并有反复边缘性溃疡、胃酸反流和远端食管狭窄。3例后来作了全胃切除加食管、空肠吻合术和胰腺部份切除术。第4例未及接受确定性手术即死亡。另2例在全胃切除、食管-十二指肠或食管-空肠吻合术及包括部份胰腺胰泌素瘤切除术
It is rare for ZES to involve the esophagus. This was initially thought to be related to gastrin which increased the pressure of the lower esophageal sphincter and the tension in the smooth muscle to prevent gastroesophageal reflux, but later many authors rejected it. This article reviewed 18 cases of esophageal lesions of ZES. MATERIALS AND METHODS: The authors retrospectively analyzed 18 patients with clinically suspected ZES from 1962 to 1983 who had complete data and were confirmed by pathology. Four patients had burning sensation of heart and difficulty swallowing 6 months to 3 years before diagnosis of ZES. Including a partial gastrectomy and gastrojejunostomy due to ulcer disease, with repeated marginal ulcers, acid reflux, and distal esophageal stenosis. Three patients underwent total gastrectomy plus esophagojejunostomy and partial pancreatic resection. The fourth case died after receiving definitive surgery. Two other cases with total gastrectomy, esophageal-duodenal or esophageal-jejunostomy, and partial resection of pancreatic myxinoma