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呼吸机相关性肺炎(VAP)是机械通气(通常指有创机械通气)48 h后至停用机械通气、拔除人工气道后48 h内发生的肺实质的感染性炎症,是机械通气患者最常出现的并发症,也是机械通气治疗失败常见原因之一。Chastre等[1]报道其发病率可高达28%,病死率高达24%~76%。Shorr等[2]报道VAP使患者的平均住院时间延长9 d,患者的医疗费用也明显增加,给社会经济带来沉重负担。因此,
Ventilator-associated pneumonia (VAP) is an infectious inflammation of the lung parenchyma that occurs 48 hours after mechanical ventilation (usually referred to as invasive mechanical ventilation) until mechanical ventilation is disabled and within 48 hours after artificial airway removal Complications that often appear are also common causes of failed mechanical ventilation. Chastre et al [1] reported that the incidence rate can be as high as 28%, the mortality rate as high as 24% to 76%. Shorr et al [2] reported that VAP prolongs the average length of stay of patients by 9 days and significantly increases the medical costs of patients and places a heavy burden on the society and economy. therefore,