Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor

• 作 者: Somchai Pinlaor Banchob Sripa
• 机 构: DepartmentofParasitology,DeparmentofPathology,PuangratYongvanit,DepartmentofSurgery,LiverFlukeandCho
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2005年30期
• 关键词: 氧化性能 DNA损伤 肝内肿瘤 肿瘤入侵 病理机制 8-Nitroguanine 8-Oxo-7 8-dihydro-2＇-deoxyguanosine H
• 基金项目: the Khon Kaen University Research Fund in Thailand，Grants-in-Aid for Scientific Research from the Ministry of Education, Science, Sports and Culture of Japan

AIM: Nitrative and oxidative DNA damage such as 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine(8-oxodG) formation has been implicated in initiation and/or promotion of inflammation-mediated carcinogenesis.The aim of this study is to clarify wh