简化门体性肝性脑病指数的临床应用

• 作 者: 贾林 李瑜元 吴惠生 余庆珠
• 机 构: 广州第一人民医院消化科
• 出 处: 世界华人消化杂志
• 发表日期: 1999年07期
• 关键词: 门体性肝性脑病指数

统计学处理计量资料和计数资料比较分别采用Ｔ检验和卡方检验，如Ｐ＜００５，表明有显著性差异．２结果２．１氟马西尼的促清醒疗效氟马西尼治疗组１２例患者中，６例Ⅰ级精神状况级别评分均由１分降至０分；４例Ⅱ级患者中有２例降至０分，１例好转为１分，另１例病情恶化为Ⅳ级，放弃治疗而死亡；２例Ⅲ级患者中１例好转为１分，另１例无效，病情恶化为Ⅳ级而死亡，治疗前后精神状况级别评分比较，Ｐ＜００５，临床有效率达１０／１２（８３３％），而醒脑静组临床有效率为２／１０（２０％），两组比较有显著性差异（Ｐ＜００５），表明氟马西尼对ＨＥ患者有较显著的醒脑作用．２．２杜秘克对ＳＨＥ的临床疗效１２例ＳＨＥ患者治疗后除１例患者无变化外，２例患者ＮＣＴ改善２级以上，９例患者ＮＣＴ至少有１级改善和（或）听觉、视觉、体感诱发电位任何一项指标有改善，临床总有效率为９１６７％（１１／１２）；ＮＣＴ改善率达８０％（８／１０）；脑诱发电位改善率达６６６７％（６／９）；３例高血氨患者的血氨水平治疗后均明显降低，有效率达１００％（３／３）；治疗前后ＰＳＥｉｎｄｅｘ比较有显著性差异（Ｐ＜００５）．３讨论随着内镜诊疗技术进展和对ＳＨＥ的重视程度以及?

Statistical analysis of measurement data and count data were compared using the T test and chi-square test, such as P <0  05, indicating significant differences. 2 Results 2.1 Flumazenil to promote the awake effect Flumazenil treatment group, 12 patients, 6 patients with grade Ⅰ mental status grade scores were reduced from 1 to 0; 4 patients with grade Ⅱ in 2 patients To 0, 1 case improved to 1 point, the other one case deteriorated to grade Ⅳ, to give up treatment and died; 2 cases of grade Ⅲ patients improved to 1 point, the other 1 case of invalid, the disease worsened to grade Ⅳ (P0005). The clinical effective rate was 10/12 (833%), while the effective rate of Xingnaojing group was 2/10 (20%). There was no significant difference between the two groups There was a significant difference (P <0  05), indicating that flumazenil in HE patients have a more significant role in brain revulation. 2.2 Du secret grams of SHE clinical efficacy of 12 cases of SHE patients after treatment except one case of patients with no change, two patients with NCT improved more than two, nine patients with at least grade 1 NCT improve and (or) auditory and visual , The somatosensory evoked potential of any one index improved, the clinical total effective rate was 9167% (11/12); NCT improvement rate of 80% (8/10); brain evoked potential improvement rate of 6667% (6 / 9). The blood ammonia levels of three patients with hypernatremia were significantly decreased after treatment, with an effective rate of 100% (3/3). There was a significant difference in PSE index before and after treatment (P <005). 3 Discussion With the progress of endoscopic diagnosis and treatment of SHE and the degree of attention?